RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-21a
RNA ID
MI0000569
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
NA
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
29361523
Title
"The feedback loop between miR-21, PDCD4 and AP-1 functions as a driving force for renal fibrogenesis"
Year
2018
Function
miR-21 is a main driving force of fibroblast activation and keeps its high expression level by employing a double negative autoregulatory loop.